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Annie Martini, D.O.

Board Certified Board Certified

  • Obstetrics and Gynecology
  • Reproductive Endocrinology and Infertility

“I LOVED working with Fertility Centers of Illinois. They are considerate, competent, and efficient. They respond to changes well and are very adaptive to requests. I have donated multiple times and this was my favorite clinic by FAR to work with.”

– Mandy B.

When they say, “Your miracle. Our mission,” it’s true. Today, we are holding our precious miracle! We are forever grateful.

I had done it all – finished college, completed grad school, traveled the world, had a successful career, and bought a house. Just shy of 40 years old, I still hadn’t found Mr. Right. But I didn’t want to give up on my dream of becoming a mother. So I decided to do it on my own.

– Anonymous patient

We have such a special bond since (our son) is Dana’s biological child, but yet I carried him through pregnancy.

– Kira and Dana, proud moms of sons Maverick and Ryker

It’s such a huge thing to even make a call for an appointment to a Fertility Clinic. While the situation is frustrating and heartbreaking, EVERYONE at FCI has been so generous, kind, and truly treats you as though you are their only patient and getting you a baby is their only goal.

– Former Patient

This location is absolutely amazing. This clinic takes the time to get to know their patients. We’ve never felt so comfortable and informed on every single detail throughout the entire process.

Biography

Annie Martini, D.O., is a Reproductive Endocrinologist board certified in both Obstetrics and Gynecology and Reproductive Endocrinology and Infertility (REI). After years of practice in Washington, D.C., she is thrilled to return to her Midwest roots.

 

Dr. Martini earned her medical degree at the Chicago College of Osteopathic Medicine, completed her residency in Obstetrics and Gynecology at Rush University Medical Center, and pursued fellowship training in Reproductive Endocrinology and Infertility at the National Institutes of Health (NIH).

 

Throughout her career, Dr. Martini has advanced fertility medicine through both clinical care and research, presenting at international conferences and publishing in respected journals. Her academic work focuses on IVF outcomes after fertility preservation. As a member of the Society for Reproductive Endocrinology and Infertility (SREI) Practice Committee, she also contributes to shaping national best practices in fertility care.

 

Dr. Martini partners closely with patients to create personalized, evidence-based plans shaped by their goals and values. She has a special interest in fertility preservation and is passionate about providing research-based guidance and compassionate support throughout each patient’s fertility journey.

 

As both a physician and a mother of two young children, Dr. Martini brings empathy, experience, and a deep appreciation for the joys and challenges of family building. Her warm, patient-centered approach is rooted in her commitment to helping each individual move closer to the family they’ve been dreaming of.

 

Dr. Martini sees patients at the Milwaukee, Wisconsin and Glenview, Illinois Fertility Centers of Illinois locations. Virtual appointments are also available.
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  • Medical School: Chicago College of Osteopathic Medicine / Midwestern University
  • Residency: Rush University Medical Center
  • Fellowship: National Institutes of Health (NIH) / NICHD / Walter Reed National Military Medical Center
  • Advocate Aurora Sinai Medical Center (Wisconsin)
  • Advocate Condell
  • Advocate Masonic
  • Advocate Lutheran
  • Endeavor Highland Park
  • Endeavor Evanston
  • Top Doctor, Washingtonian Magazine, 2024
  • ASRM Embryo Transfer Stimulation Course Certification, 2018
  • Administrative Chief Resident, Rush University Medical Center Dept. of OBGYN, 2017–2018
  • First Place Resident Research Award, Rush University Medical Center Resident Research Symposium, 2017
  • PGY-2 Medical Student Teaching Award, Rush University Medical Center Dept. of OBGYN, 2016
  • PGY-1 Medical Student Teaching Award, Rush University Medical Center Dept. of OBGYN, 2015
  • Glasgow Rubin Certificate of Academic Achievement, AMWA, 2014
  • Gold Humanism Honor Society Member, 2014
  • Psi Sigma Alpha Honor Society Member, 2014
  • PEER REVIEWED PUBLICATIONS
  • Martini AE, Beall S, Ball GD, Hayward B, Mahony MC, Collares FC, Catherino AB. Fine-Tuning the Dose of Recombinant Human Follicle-Stimulating Hormone Alfa (r-hFSH-alfa) to Individualize Treatment in Ovulation Induction and Ovarian Stimulation Cycles: A Real-World Database Analysis. Frontiers in Endocrinology. March 2023.
  • Martini AE, Dunn A, Wells L, Rollene N, Saunders R, Healy MW, Terry N, DeCherney AH, Hill MJ. “Follicle flushing does not improve live birth and increases procedure time: A systematic review and meta-analysis of randomized controlled trials.” Fertility and Sterility. March 2021. doi: 10.1016/j.fertnstert.2020.10.064. PMID: 33676753.
  • Aserlind A, Martini AE, Dong J, Zolton J, Carpinello O, DeCherney AH. “Fertility preservation before hematopoetic stem cell transplant: A case series of women with GATA2 deficiency, DOCK8 deficiency, and sickle cell disease.” Fertility and Sterility Reports. 2020. Volume 1, Issue 3, pages 287-293, ISSN 2666-3341. https://doi.org/10.1016/j.xfre.2020.10.001.
  • Martini AE. COVID-19 In Pregnancy. Global Reproductive Health. Winter 2020. Volume 5, Issue 3. Pe47 doi: 10.1097/GRH.0000000000000047.
  • Martini AE, Doyle JO. Fertility Preservation Before Deployment: Oocyte and Sperm Freezing in Members of the Active Duty Military. Semin Reprod Med. 2019 Sep;37(5-06):232-238. doi: 10.1055/s-0040-1701633. Epub 2020 Feb 10. PMID: 32040972.
  • DeAngelis AM, Martini AE, Owen CM. Assisted Reproductive Technology and Epigenetics. Semin Reprod Med. 2018 May;36(3-04):221-232. doi: 10.1055/s-0038-1675780. Epub 2019 Mar 13. PMID: 30866009.
  • Martini AE, Jasulaitis S, Fogg LF, Uhler ML, Hirshfeld-Cytron JE. Evaluating the Utility of Intralipid Infusion to Improve Live Birth Rates in Patients with Recurrent Pregnancy Loss or Recurrent Implantation Failure. J Hum Reprod Sci. 2018;11(3):261-268. doi:10.4103/jhrs.JHRS_28_18
  • Martini AE, Zolton JR, DeCherney AH. Isolated Absent Thelarche in a Patient With Neurofibromatosis Type 1 and Acromegaly. Obstet Gynecol. 2018 Jan;131(1):96-99. doi: 10.1097/AOG.0000000000002389. PMID: 29215515; PMCID: PMC5739945.
  • Martin JA, Martini AE, Molinari A, Morgan W, Ramalingam W, Buckwalter JA, McKinley TO. Mitochondrial electron transport and glycolysis are coupled in articular cartilage. Osteoarthritis Cartilage. 2012 Apr;20(4):323-9. doi: 10.1016/j.joca.2012.01.003. Epub 2012 Jan 16. PMID: 22305999; PMCID: PMC3634328.
  • BOOK CHAPTERS
  • Martini AE, Healy, MW. Polycystic Ovarian Syndrome: Impact on Adult and Fetal Health. Clinical Obstetrics and Gynecology. March 2021. Volume 64, Issue 1, p 26-32. doi: 10.1097/GRF.0000000000000593
  • Martini AE, Hill MJ. “To flush or not to flush follicles at oocyte retrieval?” Assisted Reproduction Techniques: Challenges & Management Options. 2nd edition. Wiley-Blackwell Publishing. 2020.
  • Shekhar S, Martini AE, DeCherney AH. “Genetic, Lifestyle and Environmental Factors in Male Infertility.” Newer Trends in ART. (ISBN 978-93-88958-83-7) 1st Ed. Jaypee Brothers Medical Publishers. 2019
  • ORAL ABSTRACTS AND PRESENTATIONS
  • Martini AE. “Secondary Amenorrhea/Premature Ovarian Insufficiency.” OBGYN Resident Didactics, Inova Fairfax Hospital. August, 2024. Falls Church, VA.
  • Martini AE. “Infertility evaluation and management for the generalist OBGYN.” OBGYN Grand Rounds, Inova Fairfax Hospital. May, 2024. Falls Church, VA.
  • Martini AE. “The Menstrual Cycle/Oral Contraceptives.” OBGYN Resident Didactics, Inova Fairfax Hospital. March, 2024. Falls Church, VA
  • Martini AE. “Planned Oocyte Cryopreservation.” OBGYN Grand Rounds, MedStar Washington Hospital Center. May, 2023. Washington, D.C.
  • Martini AE. “Diagnosing and Managing a Thin Endometrium.” CCRM Fertility Journal Club. December, 2022.
  • Martini AE. “Premature Ovarian Insufficiency.” OBGYN Resident Didactics, Inova Fairfax Hospital. October, 2022. Falls Church, VA.
  • Martini AE. “Elective Egg Freezing”. OBGYN Grand Rounds, Inova Fairfax Hospital. April, 2022. Falls Church, VA.
  • Martini AE. “The Menstrual Cycle.” OBGYN Resident Didactics, Inova Fairfax Hospital. October, 2021. Falls Church, VA.
  • Whiteley G, Martini AE, Jahandideh S, Devine K, Hill MJ, DeCherney AH, Doyle J, Kallen C. The impact of duration of oocyte cryopreservation on live birth outcomes in IVF cycles using autologous thawed oocytes. Presented at the American Society for Reproductive Medicine (ASRM) Meeting. October, 2021. Baltimore, MD.
  • Martini AE. “Exploring the role of ZCWPW1 in female meiosis.” Department of Reproductive Endocrinology and Infertility Fellow Thesis Defense, National Institutes of Health. June, 2021. Bethesda, MD.
  • Martini AE. “Exploring the role of ZCWPW1 in female meiosis.” Macfarlan Laboratory Meeting, Department of Intramural Research, NICHD. May, 2021. Bethesda, MD.
  • Martini AE. “Exploring the role of ZCWPW1 in female meiosis.” Affinity Group Meeting, Department of Intramural Research, NICHD. April, 2021. Bethesda, MD.
  • Martini AE. “Normal puberty.” Department of Reproductive Endocrinology and Infertility Academic Meeting, National Institutes of Health. January, 2021. Bethesda, MD.
  • Martini AE. “Exploring the role of ZCWPW1 in female meiosis.” Macfarlan Laboratory Meeting, Department of Intramural Research, NICHD. December, 2020. Bethesda, MD.
  • Martini AE. “Obese patients are less likely to pursue fertility treatment and take longer to do so after initial infertility consultation.” NICHD Scientific Retreat, National Institutes of Health. November, 2020. Bethesda, MD.
  • Martini AE. “The menstrual cycle.” Department of OB/GYN Grand Rounds, Howard University. November, 2020.
  • Martini AE. “Omega-3 fatty acids modulate the lipid profile, membrane architecture, and gene expression of leiomyoma cells (Islam et al.).” Epidemiology Journal Club, Epidemiology Branch of NICHD. November, 2020. Bethesda, MD.
  • Martini AE. “Does the endometrium play a major role in endometriosis related infertility?” Fellow presenter at ASRM Journal Club Global. November, 2020.
  • Martini AE. “Multicenter prospective study of concordance between embryo cell-free DNA and trophectoderm biopsies from 1,301 human blastocysts (Rubio et al.).” National Institutes of Health Fellowship Journal Club. August, 2020. Bethesda, MD.
  • Martini AE. “The role of ZCWPW1 in female meiosis.” Affinity Group Meeting, Department of Intramural Research, NICHD. May, 2020. Bethesda, MD.
  • Martini AE. SGFC Journal Club, Shady Grove Fertility Center. March, 2020. Rockville, MD.
  • Martini AE. “Procedures in REI.” Department of OB/GYN Grand Rounds, Howard University. February, 2020. Washington, DC.
  • Martini AE. “Ovarian function and disease states.” Department of Reproductive Endocrinology and Infertility Academic Meeting, National Institutes of Health. January, 2020. Bethesda, MD.
  • Martini AE. “Embryonic cell-free DNA versus trophectoderm biopsy for aneuploidy testing: concordance rate and clinical implications (Rubio et al.).” National Institutes of Health Fellowship Journal Club. December, 2019. Bethesda, MD.
  • Martini AE. “Obesity in Reproduction.” SGFC Practice Meeting, Shady Grove Fertility Center. August, 2019. Rockville, MD.
  • Martini AE. “Contraception.” Department of Reproductive Endocrinology and Infertility academic meeting, National Institutes of Health. June, 2019. Bethesda, MD.
  • Martini AE. “Understanding the role of ZCWPW1 in meiotic recombination in female gametes.” Department of Reproductive Endocrinology and Infertility Research in Progress Meeting, National Institutes of Health. May, 2019. Bethesda, MD.
  • Martini AE. “Differential gene expression during placentation in pregnancies conceived with different fertility treatments compared with spontaneous pregnancies (Lee et al.)” and “Oral dydrogesterone versus intravaginal micronized progesterone gel for luteal phase support in IVF: a randomized clinical trial (Griesinger et al.)” National Institutes of Health Fellowship Journal Club. May, 2019. Bethesda, MD.
  • Martini AE. “Business models and provider satisfaction in in vitro fertilization centers in the USA (McLaughlin et al.)” Epidemiology Journal Club, Epidemiology Branch of NICHD. January, 2019. Bethesda, MD.
  • Martini AE. “Oral Contraceptives” Department of Adult Endocrinology Academic Meeting, National Institutes of Health, December, 2018. Bethesda, MD.
  • Martini AE. “Evaluating the Utility of Intralipid Infusion in Patients with Recurrent Pregnancy Loss (RPL) or Recurrent Implantation Failure (RIF): Does it Improve Live Birth Rates and is it Cost Effective?” Rush OB/GYN 42nd Annual Resident Research Symposium. April 2017. Chicago, IL
  • Martini AE. “Preimplantation Genetics.” OBGYN Grand Rounds, Rush University Medical Center. October 2017. Chicago, IL.
  • Martini AE. “Recurrent Pregnancy Loss.” OBGYN Grand Rounds, Rush University Medical Center. July 2016. Chicago, IL.
  • Martini AE. “Twin-Twin Transfusion.” NorthShore Perinatal Conference. October 2013. Evanston, IL.
  • POSTER PRESENTATIONS
  • Martini AE, Whiteley G, Jahandideh S, Eubanks A, Devine K, Brauer A, Widra E, Hill MJ, DeCherney AH, Doyle J, Kallen C. The impact of ethnicity on outcomes in autologous oocyte cryopreservation/thaw cycles. Presented at the American Society for Reproductive Medicine (ASRM) Meeting. October, 2021.
  • Martini AE, Jahandideh S, Williams A, Devine K, Widra E, Hill MJ, DeCherney AH, O’Brien J. Trends in elective egg freezing before and after the COVID-19 pandemic. Presented at the American Society for Reproductive Medicine (ASRM) Meeting. October, 2021.
  • Martini AE, Dunn A, Rollene N, Saunders R, Hill MJ. Follicle flushing does not improve live birth and reduces oocyte yield: A meta-analysis. Presented at the American College of Obstetricians and Gynecologists (ACOG) Armed Forced District Virtual Meeting. October, 2020.
  • Martini AE, Dunn A, Wells L, Rollene N, Saunders R, Healy MW, Terry N, DeCherney AH, Hill MJ. Follicle flushing does not improve live birth and reduces oocyte yield: A systematic review and meta-analysis of randomized controlled trials (RCTs). Presented at the 75th American Society of Reproductive Medicine (ASRM) Virtual Congress. October, 2020.
  • Martini AE, Kwal J, Jahandideh S, Devine K, Hill MJ, DeCherney AH, Durso N. Obese patients are less likely to pursue fertility treatment and take a longer time to do so, after initial infertility consultation. Presented at the 75th American Society of Reproductive Medicine (ASRM) Virtual Congress. October, 2020.
  • Martini AE, Kodama S, Na T, Jahandideh S, Hill MJ, DeCherney AH, Devine K, Chang F. East Asian women experience lower rates of live birth than Caucasian women after single fresh blastocyst transfer but have similar outcomes after frozen transfer. Presented at the 75th American Society of Reproductive Medicine (ASRM) Virtual Congress. October, 2020.
  • Martini AE, Beall S, Mottla GL, Ball GD, Hayward B, Mahony MC, Catherino AB. Fine Tuning of Recombinant Human Follicle-Stimulating Hormone (r-hFSH) Dose to Individualize Treatment: Real-World Database Analysis of Ovulation Induction Cycles For Natural Or Intrauterine Insemination. Presented at the 75th American Society of Reproductive Medicine (ASRM) Virtual Congress. October, 2020.
  • Ball GD, Martini AE, Beall S, Mottla GL, Hayward B, Mahony MC, Catherino AB. Frozen embryo transfer cycles may offer advantage in both pregnancy success and reducing the number of patients discontinuing care. Presented at the 75th American Society of Reproductive Medicine (ASRM) Virtual Congress. October, 2020.
  • Martini AE, Jahandideh S, Devine K, Hill MJ, DeCherney AH, Doyle JO, Chang F. African American ethnicity does not negatively impact live birth rates in in-vitro fertilization cycles utilizing autologous vitrified/warmed oocytes. Accepted for presentation at the Society of Reproductive Investigation (SRI) 67thAnnual Scientific Meeting. March, 2020. Vancouver, British Columbia. (Accepted but conference canceled due to COVID-19)
  • Martini AE, Horowitz R, Devine K, Tsai JH, Hill MJ, DeCherney AH, Doyle JO, Kallen CB. Live Birth Data From 498 Elective and Non-Elective Autologous Oocyte Thaw Cycles (2009-2018). Presented at the 74th American Society of Reproductive Medicine (ASRM) Scientific Congress. October, 2019. Philadelphia, PA.
  • Purmalek M, Martini AE, Hill MJ. Assessing the Probability of Clinical Pregnancy and Live Birth in Recipients of Donor Oocytes Based on Donor Oocyte Lot Size. Presented at the American College of Obstetricians and Gynecologists (ACOG) Armed Forced District Annual Meeting. September, 2019. San Diego, CA.
  • Martini AE, Richter K, Hayes H, Tucker M, Devine K, Levy M, DeCherney AH, Hill MJ, Doyle N. The Probability of Clinical Pregnancy in Recipients of Donor Oocytes is Dependent Upon Donor Oocyte Lot Size. Presented at the Society of Reproductive Investigation (SRI) 66th Annual Scientific Meeting. March, 2019. Paris, France.
  • Martini AE, Hammer K, Heller B, Hirshfeld-Cytron JE. “The Impact of In-Person and Online Structured Yoga Programs on Anxiety Levels in Patients After In Vitro Fertilization (IVF) Failure: A Preliminary Analysis.” Presented at the 73rd American Society of Reproductive Medicine (ASRM) Scientific Congress. October, 2017. San Antonio, TX.
  • Hirshfeld-Cytron JE, Martini AE, Jasulaitis S, Uhler ML. “Do Intralipids Improve Outcomes in Recurrent Pregnancy Loss (RPL)/Recurrent Implantation Failure (RIF) Patients Undergoing IVF? Is it cost effective?” 72nd American Society of Reproductive Medicine (ASRM) Scientific Congress. October, 2016. Salt Lake City, UT.
  • Martini AE, Garlanger K, Heinking K. “Iliosacral Dysfunction is Correlated With Incidence of Lower Extremity Injury in High School Athletes.” Midwestern University Kenneth A. Suarez Annual Research Day. May, 2012. Downers Grove, IL.
  • Martini AE, Martin JA, Buckwalter JA. Rotenone inhibits ATP and oxidant production in articular cartilage. Osteoarthritis Research Society International (OARSI) World Congress on Osteoarthritis. September, 2010. Brussels, Belgium.
  • Martini AE, Ramalingam W, Martin JA, Buckwalter JA. Effects of chronic rotenone treatment on cartilage responses to impact injury. Annual Meeting of the Orthopaedic Research Society. March, 2010. New Orleans, LA. Martin JA, Martini AE, Walter M, Buckwalter JA. Rotenone treatment impairs biosynthetic activity in articular cartilage. Osteoarthritis Research Society International (OARSI) World Congress on Osteoarthritis. September, 2009. Quebec, Canada

Q&A

I appreciate that no two days are the same—each patient brings a new story, a new challenge, and a chance to think creatively. The field itself is constantly evolving, and staying on the leading edge of reproductive science keeps the work dynamic and intellectually engaging. Most of all, knowing that I’m helping someone take meaningful steps toward building their family—something I deeply value in my own life—makes the work incredibly rewarding.

It was the science that first drew me in. I’ve always been fascinated by how intricately the body is guided by hormones. But what truly confirmed that this was the right field for me was seeing how that science is applied in practice. Meeting couples, hearing their stories, and partnering with them to create thoughtful, personalized plans—grounded in evidence but shaped by their individual journeys—has been the most meaningful part of this work.

Taking time to understand each couple’s unique journey and goals to create a personalized plan forward is deeply fulfilling. And when those efforts lead to the family they dreamed of—whether it’s through meeting their baby or seeing a photo—it’s a profound reminder of how meaningful this work truly is.

I’m most proud of the relationships I build with my patients. I make it a point to understand who they are beyond the medical context. Getting to know my patients on a personal level helps me provide care that is truly tailored to their needs and values.

I’ve always been especially interested in fertility preservation, particularly egg freezing. The decision to freeze eggs is often a complex one, both emotionally and logistically, but it can also be incredibly empowering. The science behind freezing and thawing eggs is intricate, and I’ve researched IVF outcomes in couples using previously frozen eggs. I believe understanding this science—and setting appropriate expectations for patients pursuing this path—is critically important.

I encourage my patients to view challenges as hurdles—not roadblocks. Even when it feels like the odds are insurmountable, the vast majority of the time, we’re able to find a way forward. With the right support and medical care, we can often overcome those hurdles and help build the family they’ve been dreaming of.

I spend time with family and friends, hiking, listening to podcasts, gardening and flower arranging.

I used to teach a mixed martial arts fitness class called Body Combat! To me, it was more than just an incredible workout—it was a tight-knit community that meant a lot to me. It was also during that time that my interest in OBGYN and REI began to take shape. I credit part of my path to becoming a reproductive health provider to those years of teaching and connecting with that community.

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